PYSEC-2026-1224 Boltz contains an insecure deserialization vulnerability in its molecule loading functionality

Boltz 2.0.0 contains an insecure deserialization vulnerability in its molecule loading functionality. The application uses Python pickle to deserialize molecule data files without validation. An attacker with the ability to place a malicious pickle file in a directory processed by boltz can achie...

Tendenci Affected by Authenticated Remote Code Execution via Pickle Deserialization

A critical deserialization vulnerability exists in Tendenci Helpdesk module NOTE, by default, Helpdesk is NOT enabled, affecting the version 15.3.11 and earlier. This vulnerability allows remote code execution RCE by an authenticated user with staff security level due to using Python's pickle...

PYSEC-2026-1950 Tendenci Affected by Authenticated Remote Code Execution via Pickle Deserialization

A critical deserialization vulnerability exists in Tendenci Helpdesk module NOTE, by default, Helpdesk is NOT enabled, affecting the version 15.3.11 and earlier. This vulnerability allows remote code execution RCE by an authenticated user with staff security level due to using Python's pickle...

PYSEC-2026-1373 Fickling has a bypass via runpy.run_path() and runpy.run_module()

Fickling's assessment runpy was added to the list of unsafe imports https://github.com/trailofbits/fickling/commit/9a2b3f89bd0598b528d62c10a64c1986fcb09f66. Original report Summary Fickling versions up to and including 0.1.6 do not treat Python’s runpy module as unsafe. Because of this, a malicio...

PYSEC-2026-1371 Fickling Blocklist Bypass: cProfile.run()

Fickling's assessment cProfile was added to the list of unsafe imports https://github.com/trailofbits/fickling/commit/dc8ae12966edee27a78fe05c5745171a2b138d43. Original report Description Summary Fickling versions up to and including 0.1.6 do not treat Python's cProfile module as unsafe. Because ...

PYSEC-2026-1787 picklescan has Arbitrary file read using `io.FileIO`

Summary Unsafe pickle deserialization allows unauthenticated attackers to read arbitrary server files and perform SSRF. By chaining io.FileIO and urllib.request.urlopen, an attacker can bypass RCE-focused blocklists to exfiltrate sensitive data example: /etc/passwd to an external server. Details...

PYSEC-2026-1782 Picklescan does not block ctypes

Summary Picklescan doesnt flag ctypes module as a dangerous module, which is a huge issue. ctypes is basically a foreign function interface library and can be used to Load DLLs Call C functions directly Manipulate memory raw pointers. This can allow attackers to achieve RCE by invoking direct...

Picklescan vulnerable to Arbitrary File Writing

SummaryPicklescan has got open and shutil in its default dangerous blocklist to prevent arbitrary file overwrites. However the module distutils isnt blocked and can be used for the same purpose ie to write arbitrary files. DetailsThis is another vulnerability which impacts the downstream user.By...

PYSEC-2026-1785 Picklescan has Incomplete List of Disallowed Inputs

Summary Currently picklescanner only blocks some specific functions of the pydoc and operator modules. Attackers can use other functions within these allowed modules to go through undetected and achieve RCE on the final user. Particularly pydoc.locate: Can dynamically resolve and import arbitrary...

PYSEC-2026-1791 Picklescan vulnerable to Arbitrary File Writing

Summary Picklescan has got open and shutil in its default dangerous blocklist to prevent arbitrary file overwrites. However the module distutils isnt blocked and can be used for the same purpose ie to write arbitrary files. Details This is another vulnerability which impacts the downstream user. ...

PYSEC-2026-1790 Picklescan Bypasses Unsafe Globals Check using pty.spawn

Summary The vulnerability allows malicious actors to bypass PickleScan's unsafe globals check, leading to potential arbitrary code execution. The issue stems from the absence of the pty library more specifically, of the pty.spawn function from PickleScan's list of unsafe globals. This vulnerabili...

PYSEC-2026-1762 Arbitrary Code Execution in pdfminer.six via Crafted PDF Input

Summary pdfminer.six will execute arbitrary code from a malicious pickle file if provided with a malicious PDF file. The CMapDB.loaddata function in pdfminer.six uses pickle.loads to deserialize pickle files. These pickle files are supposed to be part of the pdfminer.six distribution stored in th...

PYSEC-2026-1761 Insecure Deserialization (pickle) in pdfminer.six CMap Loader — Local Privesc

🚀 Overview This report demonstrates a real-world privilege escalation vulnerability in pdfminer.six due to unsafe usage of Python's pickle module for CMap file loading. It shows how a low-privileged user can gain root access or escalate to any service account by exploiting insecure deserializatio...

PYSEC-2026-1399 Fugue is Vulnerable to Remote Code Execution by Pickle Deserialization via FlaskRPCServer

Summary The Fugue framework implements an RPC server system for distributed computing operations. In the core functionality of the RPC server implementation, I found that the decode function in fugue/rpc/flask.py directly uses cloudpickle.loads to deserialize data without any sanitization. This...

PYSEC-2026-1282 cryptidy allows code execution via untrusted data due to pickle.loads

cryptidy through 1.2.4 allows code execution via untrusted data because pickle.loads is used. This occurs in aesdecryptmessage in symmetricencryption.py...

PYSEC-2026-1854 python-socketio vulnerable to arbitrary Python code execution (RCE) through malicious pickle deserialization in certain multi-server deployments

Summary A remote code execution vulnerability in python-socketio versions prior to 5.14.0 allows attackers to execute arbitrary Python code through malicious pickle deserialization in multi-server deployments on which the attacker previously gained access to the message queue that the servers use...

Picklescan has a missing detection when calling built-in python idlelib.autocomplete.AutoComplete.get_entity

SummaryUsing idlelib.autocomplete.AutoComplete.getentity, which is a built-in python library function to execute remote pickle file. DetailsThe attack payload executes in the following steps:First, the attacker craft the payload by calling to idlelib.autocomplete.AutoComplete.getentity function i...

PYSEC-2026-1784 Picklescan has a missing detection when calling built-in python idlelib.autocomplete.AutoComplete.get_entity

Summary Using idlelib.autocomplete.AutoComplete.getentity, which is a built-in python library function to execute remote pickle file. Details The attack payload executes in the following steps: First, the attacker craft the payload by calling to idlelib.autocomplete.AutoComplete.getentity functio...

PYSEC-2026-1792 Picklescan is missing detection when calling built-in python ensurepip._run_pip

Summary Using ensurepip.runpip function, which is a built-in python library function to execute remote pickle file. Details The attack payload executes in the following steps: First, the attacker craft the payload by calling to ensurepip.runpip function in reduce method Then when the victim after...

PYSEC-2026-1781 Picklescan has a missing detection when calling built-in python idlelib.debugobj.ObjectTreeItem

Summary Using idlelib.debugobj.ObjectTreeItem.SetText, which is a built-in python library function to execute remote pickle file. Details The attack payload executes in the following steps: First, the attacker craft the payload by calling to idlelib.debugobj.ObjectTreeItem.SetText function in...