CVE-2026-31972

SAMtools is a program for reading, manipulating and writing bioinformatics file formats. The mpileup command outputs DNA sequences that have been aligned against a known reference. On each output line it writes the reference position, optionally the reference DNA base at that position obtained fr...

CVE-2026-31973 NULL pointer dereference in samtools cram-size

SAMtools is a program for reading, manipulating and writing bioinformatics file formats. Starting in version 1.17, in the cram-size command, used to write information about how well CRAM files are compressed, a check to see if the cramdecodecompressionheader was missing. If the function returned ...

CVE-2026-31972

SAMtools mpileup contains a memory-management bug where reference data could be discarded too early, causing use-after-free reads. This could leak information about program state and may crash the process. The issue is fixed in SAMtools versions 1.21.1 and 1.22. No exploit details are provided in...

EUVD-2026-12944

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the BYTEARRAYSTOP method, an out-by-one error in the...

EUVD-2026-12934

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the cramdecodeslice function called while reading CRAM records, validation of the reference id field occurred too late, allowing two out of bounds read...